Wet wipes comprising a lotion

ABSTRACT

Described herein is a wet wipe including a substrate and a lotion. The substrate includes from about 55% to about 85% polyester. The lotion includes (a) from about 98.5% to about 99.5% water; (b) from about 0.055% to about 0.1% of an organic acid; and (c) a pH buffering system. The lotion has a pH from about 3.6 to about 4.8.

FIELD

Described herein is a wet wipe comprising a substrate and a lotion,wherein the lotion is resistant to bacteria, mold, and/or yeast growth.

BACKGROUND

Wet wipes are constructed from porous or absorbent sheets impregnatedwith a lotion and they are sold and stored in an air-tight container orwrapper to prevent the sheets drying out. Wet wipes are made for avariety of uses. The two main categories of use are firstly, those forgeneral household cleaning tasks, such as the cleaning of hard surfaceslike floors or kitchen surfaces and secondly, those made for personalcleansing, such as the removal of make-up, or the cleaning of infantsprior to the fitting of a new diaper or the simple refreshment of theskin after meals or while traveling. Wipes have also found use withfeminine health and adult incontinence products.

A major proportion of the wipes intended for the cleansing of human skinare wet wipes which are designed for use with infants and youngchildren. They are particularly used by parents during the changing ofbabies to clear away any excess fecal or urine residues in the peri-analregion before applying a fresh diaper or nappy. Wet wipes are requiredto be effective at cleaning while at the same time being very gentle andmild on the skin of the baby. This is especially important given thatthe skin of the baby around the genitals and anus may become verysensitive or rash-prone after extended contact with urine and fecalmatter.

One way to formulate a gentle and mild lotion for a wet wipe is toincrease the water content of the lotion. Increasing the water contentof the lotion has the added benefit of decreasing the amount ofchemicals applied to the skin. However, the higher the water content ofa lotion, the more difficult it is to meet preservative system efficacyrequirements for microbial growth.

Therefore, there is a need for a wet wipe comprising a gentle, highwater content lotion that meets preservative system efficacyrequirements for microbial growth. More specifically, there is a needfor a wet wipe comprising a gentle, 99% water lotion that meetspreservative system efficacy requirements for microbial growth.

SUMMARY OF THE INVENTION

Described herein is a wet wipe comprising a substrate and a lotion,wherein the substrate comprises from about 55% to about 85% polyester byweight of the substrate, and wherein the lotion comprises (a) from about98.5% to about 99.5% water by weight of the lotion; (b) from about0.055% to about 0.1% of an organic acid according to a HPLC test methoddescribed herein; and (c) a pH buffering system; wherein the lotion hasa pH from about 3.6 to about 4.8.

Also described herein is a wet wipe comprising a substrate and a lotion,wherein the substrate comprises from about 55% to about 85% polyester byweight of the substrate, wherein the substrate comprises from about14.5% to about 45% cotton by weight of the substrate, wherein the lotioncomprises from about 98.5% to about 99.5% water by weight of the lotion,and wherein the lotion has an Equivalence Point from about 10 to about50.

Also described herein is a package comprising a plurality of wet wipes,wherein the plurality of wet wipes each comprise a substrate and alotion, wherein the substrate comprises (a) from about 55% to about 85%polyester by weight of the substrate; and (b) from about 14.5% to about45% cotton by weight of the substrate; wherein the cotton is devoid ofchlorine; wherein the lotion comprises (a) from about 98.5% to about99.5% water by weight of the lotion; (b) from about 0.055% to about 0.1%of an organic acid according to a HPLC test method described herein; and(c) from about 0.4% to about 1% of a pH buffering system by weight ofthe lotion; wherein the organic acid is selected from the groupconsisting of anisic acid, malic acid, lactic acid, dehydroacetic acid,gluconic acid, salicylic acid, benzoic acid, sorbic acid, levulinicacid, and mixtures thereof; wherein the lotion has a pH from about 3.6to about 4.4; wherein the lotion has an Equivalence Point from about 15to about 40; and wherein the lotion is devoid of fragrance and/orperfume.

DETAILED DESCRIPTION

The following definitions may be useful in understanding the presentdisclosure:

“Devoid of,” “free of,” and the like, as those terms are used herein,means that the wet wipe, lotion, and/or substrate does not have morethan trace amounts of background levels of a given material, ingredient,or characteristic following these qualifiers; the amount of the materialor ingredient does not cause harm or irritation that consumers typicallyassociate with the material or ingredient; or the material or ingredientwas not added to the wet wipe, lotion, and/or substrate intentionally.In some instances, “devoid of” and “free of” can mean there is nomeasurable amount of the material or ingredient. For example, the wetwipe in some forms contains no measurable amounts of chlorine.

“Soil” refers herein to matter that is extraneous to a surface beingcleaned. For example, soils include body exudates, household matter, andoutdoor matter. Body exudates include feces, menses, urine, vomitus,mucus, and the like. Household matter includes food, beverages,combinations thereof, and the like. Outdoor matter includes dirt, mud,snow, paint, crayons, and the like.

“Nonwoven” refers herein to a fibrous structure made from an assembly ofcontinuous fibers, coextruded fibers, non-continuous fibers andcombinations thereof, without weaving or knitting, by processes such asspunbonding, carding, meltblowing, airlaying, wetlaying, coforming, orother such processes known in the art for such purposes.

“Substrate” refers herein to a material which is primarilytwo-dimensional (i.e. in an XY plane) and whose thickness (in a Zdirection) is relatively small (i.e. 1/10 or less) in comparison to thesubstrate's length (in an X direction) and width (in a Y direction).Non-limiting examples of substrates include a web, layer or layers orfibrous materials, nonwovens, films and foils such as polymeric films ormetallic foils. These materials may be used alone or may comprise two ormore layers joined together. As such, a web is a substrate.

“Wipe” refers herein to a piece of material, generally non-wovenmaterial, used in cleansing hard surfaces, food, inanimate objects, toysand body parts. In particular, many currently available wipes may beintended for the cleansing of the perianal area after defecation.

As used herein, percentages are given as the weight of the component tothe total weight of the lotion, unless otherwise indicated. Percentagesreflect 100% active component material. For example, if a component isavailable in a dispersion at a concentration of 50% component todispersion, by weight, twice as much of the dispersion, by weight, wouldbe added to the lotion to provide the equivalent of 100% activecomponent.

Values disclosed herein as ends of ranges are not to be understood asbeing strictly limited to the exact numerical values recited. Instead,unless otherwise specified, each numerical range is intended to meanboth the recited values and any integers within the range. For example arange disclosed as “1 to 10” is intended to mean “1, 2, 3, 4, 5, 6, 7,8, 9, 10.”

As used herein, the articles “a” and “an” when used herein, for example,“an anionic emulsifier” or “a fiber” is understood to mean one or moreof the material that is claimed or described.

The wet wipe described herein comprises a lotion. The lotion describedherein comprises from about 98% water to about 99.9% water,alternatively from about 98.5% water to about 99.7% water, alternativelyfrom about 98.5% water to about 99.5% water, alternatively from about99% water to about 99.3% water, by weight of the lotion. At such a highwater content, the lotion described herein must comprise a strongpreservative system for preventing microbial growth. The percent waterin the lotion can be calculated using the Water Content Method providedherein.

The lotion described herein may be incorporated onto a substrate at aload of about 200% to about 600%, alternatively from about 300% to about500%, and alternatively from about 325% to about 460%, by weight of thesubstrate.

The lotions described herein, and wipes comprising the lotions, may bemade by the conventional processes described in the art. Alternatively,the lotions and wipes are made according to U.S. Pat. No. 7,365,030entitled “Process for making a wet wipe using a concentrated emulsion”by Sylvie Chamba et al., which is incorporated herein by reference.

Lotion Preservative System

Controlling microbiological growth is a necessary function of wet wipes,especially wet wipes comprising a high water content lotion. To controlmicrobiological growth, the lotion described herein comprises apreservative system. The preservative system may include a preservativeenhancing agent and one or more preservatives. A preservative may beunderstood to be a chemical or natural compound or a combination ofcompounds reducing the growth of microorganisms, thus enabling a longershelf life for a package of wet wipes (opened or not opened) as well ascreating an environment with reduced growth of microorganisms whentransferred to the skin during the wiping process.

The spectrum of activity of the preservative may include bacteria,molds, and/or yeast. Each of such microorganisms may be killed by thepreservative. Another mode of action to be contemplated may be thereduction of the growth rate of the microorganisms without activekilling. Both actions however result in a drastic reduction of thepopulation of microorganisms.

The lotion described herein comprises a preservative which is an organicacid. The lotion comprises at least 0.055%, alternatively at least0.06%, alternatively at least 0.07%, alternatively from about 0.05% toabout 0.6%, alternatively from about 0.05% to about 0.4%, alternativelyfrom about 0.05% to about 0.3%, alternatively from about 0.055% to about0.1%, alternatively from about 0.08% to about 0.4%, alternatively fromabout 0.2% to about 0.3%, alternatively from about 0.06% to about0.085%, and alternatively from about 0.07% to about 0.084% of theorganic acid by weight of the lotion, according to the HPLC test methoddescribed herein. The organic acid may be selected from the groupconsisting of anisic acid, malic acid, lactic acid, dehydroacetic acid,gluconic acid, salicylic acid, benzoic acid, sorbic acid, levulinicacid, and mixtures thereof. Alternatively, the organic acid may bebenzoic acid or sorbic acid. Alternatively, the organic acid may bebenzoic acid. Salts of organic acids may also be present in the lotiondescribed herein. Exemplary salts of organic acids include sodiumbenzoate, sodium gluconate, sodium levulinate, sodium anisate, and/orpotassium sorbate. The percent organic acid in the lotion can becalculated using the Organic Acid Content Test Methods provided herein.

The organic acids described herein are organic compounds with acidicproperties. The most common organic acids are carboxylic acids, whoseacidity is associated with a carboxyl group —COOH. In general, organicacids are weak acids that dissociate in an aqueous solution to achieveequilibrium. The percent dissociation can be defined as the ratio of theamount of acid dissociated to the initial concentration of acid,multiplied by 100. The percent dissociation can be calculated based onthe pKa of the weak acid and the pH of the aqueous solution. As anexample, when sodium benzoate is formulated into an aqueous lotioncomposition, it forms an equilibrium between sodium benzoate and benzoicacid based on its pKa of 4.2 and on the pH of the aqueous lotioncomposition. At a pH of 4.2, there is 50% sodium benzoate and 50%benzoic acid in the lotion composition.

Without being bound by theory, it is believed that different organicacids present in a wipe lotion may interact to different degrees withthe various kinds of nonwoven fibers that are present in a wipesubstrate, once the wipe lotion is impregnated into the substrate andremains there until consumer usage. Different kinds of interactions mayoccur based on the physical and chemical properties of the organic acidand of the nonwoven fiber. These interactions may lead to absorption ofthe organic acid to the surface of the fiber or to absorption of theorganic acid into the structure of the fiber.

Hansen's solubility parameters are a way of predicting if one materialwill want to interact with and potentially dissolve in another material.Each molecule is given three Hansen parameters, one for the dispersionforces between molecules, one for the dipolar intermolecular forcebetween molecules, and one for the hydrogen bonding between molecules.These parameters serve as co-ordinates for a point in three dimensionsknown as the Hansen space. The nearer two molecules are in thisthree-dimensional space, the more compatible they are, the more likelythey are to interact, and the greater the potential for them to dissolvein each other.

In the case of polyester fibers, certain organic acids such as benzoicacid share physical and chemical similarities to polyester that causethem to have a fairly similar Hansen space. This means that, over time,while the wipe lotion is in contact with wipe substrate comprisingpolyester fibers, certain organic acids such as benzoic acid willinteract with and even be absorbed into the polyester fibers, reducingtheir concentration in the wipe lotion and hence making them unavailableto participate in preservative system efficacy.

The preservative system of the lotion described herein may includeadditional compounds, for example chelating agents, such asethylenediamine tetraacetic acid (EDTA) and its salts, or diethylenetriamine pentaacetic acid (DTPA) and its salts, or gluconic acid and itssalts. The chelating agent may be disodium EDTA or sodium gluconate.

The lotion described herein may be incorporated into a substrate at aload of about 200% to about 600%, alternatively from about 325% to about460%, by weight of the substrate. The substrate may be a nonwovenmaterial.

The preservative system in the lotion described herein may include oneor more preservative enhancing agents. Exemplary preservative enhancingagents include sorbitan caprylate, glyceryl caprylate/caprate, orcombinations thereof. An exemplary sorbitan caprylate is manufactured byClariant under the designation VELSAN® SC. An exemplary glycerylcaprylate/caprate may be CremerCOOR® GC810, CremerCOOR® GCB, or IMWITOR®742, all available from Peter Cremer, or CAPMUL® 708G, available fromAbitec.

The lotion described herein may comprise from about 0.05% to about0.25%, alternatively from about 0.07% to about 0.22%, alternatively fromabout 0.09% to about 0.2%, alternatively from about 0.11% to about0.18%, and alternatively from about 0.14% to about 0.18% of apreservative enhancing agent by weight of the lotion.

Lotion Buffering System

The lotion described herein comprises from about 0.3% to about 1%,alternatively from about 0.4% to about 1%, alternatively from about 0.5%to about 0.85%, and alternatively from about 0.6% to about 0.75% of a pHbuffering system, by weight of the lotion, which also may help preventand/or reduce the growth of bacteria, mold, and/or yeast. The pHbuffering system may be a citrate-citric acid buffering system at a pHof less than 5. The pH buffering system may be a citrate-citric acidbuffering system at a pH of less than 4. The pH buffering system may bea sodium citrate-citric acid buffering system at a pH of less than 5.The pH buffering system may be a sodium citrate-citric acid bufferingsystem at a pH of less than 4. The pH buffering system may comprisesodium citrate dihydrate and citric acid anhydrous. The lotion describedherein may have a pH from about 3.5 to about 7, alternatively from about3.5 to about 6, alternatively from about 3.6 to about 4.8, alternativelyfrom about 3.6 to about 4.4, alternatively from about 3.6 to about 4.2,and alternatively from about 3.8 to about 4.2.

The lotion described herein may have an Equivalence Value from about 25to about 100, alternatively from about 30 to about 95, alternativelyfrom about 55 to about 90, alternatively from about 65 to about 90,alternatively from about 60 to about 80, alternatively from about 62 toabout 75, and alternatively from about 65 to about 70, according to theBuffering Capacity Test Method described herein.

A lotion having a higher Equivalence Value, such as from about 65 toabout 90, may be desired because it can help to protect a baby's skinagainst irritation caused by feces and urine residue that can remainafter cleaning. The proteases in feces that damage the skin can start tobecome active around pH 5 and can reach peak activity between pH 7 to 8.Urea in urine may be converted to ammonia by bacteria on the skin,elevating the pH and making the fecal proteases more active. Bydepositing a lotion with a higher Equivalence Value on the skin, anacidic buffer may be created that resists the climb in pH that wouldnormally occur over time when trace amounts of feces and urine arepresent. By resisting the climb in pH, a lotion with a higherEquivalence Value can protect the skin from damage caused by fecalproteases and reduce the likelihood that rash will occur between diaperchanges.

The lotion described herein may be devoid of phenoxyethanol.

Lotion Optional Ingredients

The lotion described herein may include various optional ingredients,such as surfactants, emollients, colorants, opacifying agents,film-formers, soothing agents, skin protectants, medically activeingredients, healing actives, and the like, such as described in U.S.Pat. Nos. 7,666,827; 7,005,557; 8,221,774; and U.S. Patent ApplicationPublication No. 2011/0268777.

The lotion described herein may comprise an emollient. Emollients may(1) hydrate soil residues (for example, fecal residues or dried urineresidues or menses residues), thus enhancing their removal from theskin, (2) hydrate the skin, thus reducing its dryness and irritation,(3) protect the skin from later irritation (for example, caused by thefriction of an absorbent article) as the emollient is deposited onto theskin and remains at its surface as a thin protective layer, and (4)provide a desired sensory feel to the lotion and/or the skin.

The emollient may include silicone oils, functionalized silicone oils,hydrocarbon oils, fatty alcohols, fatty alcohol ethers, fatty acids,esters of monobasic and/or dibasic and/or tribasic and/or polybasiccarboxylic acids with mono and polyhydric alcohols, polyoxyethylenes,polyoxypropylenes, mixtures of polyoxyethylene and polyoxypropyleneethers of fatty alcohols, and mixtures thereof. The emollients may beeither saturated or unsaturated, have an aliphatic character and bestraight or branched chained or contain alicyclic or aromatic rings.

The lotion described herein may comprise a mixture of caprylic/caprictriglycerides in combination with Bis-PEG/PPG-16/16 PEG/PPG-16/16dimethicone known as ABIL® CARE 85, available from Evonik Industries.

The lotion described herein may include one or more surfactants. Thesurfactant may be an individual surfactant or a mixture of surfactants.The surfactant may be a polymeric surfactant or a non-polymeric one. Thesurfactant or combinations of surfactants may be mild, which means thatthe surfactants provide sufficient cleaning or detersive benefits but donot overly dry or otherwise harm or damage the skin. The surfactant,when present in the lotion, may be present in an amount ranging fromabout 0.05% to about 1%, alternatively from about 0.075% to about 0.5%,alternatively from about 0.1% to about 0.2%, and alternatively fromabout 0.15% to about 0.2% by weight of the lotion. The surfactant maycomprise PEG-40 Hydrogenated Castor Oil (PEG-40 HCO), such as EMULSOGEN®HCW049 manufactured by Clariant. The surfactant may comprise apolyglyceryl ester or a mixture of polyglyceryl esters.

The lotion described herein may comprise one or more rheology modifiers.A rheology modifier may help to stabilize the lotion by reducing orpreventing coalescence of droplets of the hydrophobic materials in thecomposition.

Non-limiting examples of rheology modifiers include, but are not limitedto, hydrocolloids, including natural gums, such as xanthan gum. Thelotion described herein may comprise from about 0.01% to about 0.1%,alternatively from about 0.03 to about 0.08%, alternatively from about0.05% to about 0.07%, and alternatively about 0.06% of a rheologymodifier by weight of the lotion.

The wet wipe and/or lotion described herein may be devoid of fragranceand/or perfume.

Wet Wipe Substrate

The lotion described herein may be loaded onto a substrate to form a wetwipe. The substrate may be a nonwoven material. The nonwoven materialmay comprise one or more layers of fibrous structures, wherein eachlayer may include continuous fibers, coextruded fibers, non-continuousfibers, and combinations thereof.

The substrate described herein comprises from about 5% to about 100%,alternatively from about 15% to about 95%, alternatively from about 25%to about 90%, alternatively from about 35% to about 90%, alternativelyfrom about 45% to about 85%, alternatively from about 50% to about 80%,alternatively from about 55% to about 75%, alternatively from about 65%to about 75% polyester, by weight of the substrate. The polyester maycomprise less than 100 ppm antimony or the polyester may be devoid ofantimony.

The substrate described herein comprises from about 14.5% to about 100%,alternatively from about 14.5% to about 95%, alternatively from about14.5% to about 75%, alternatively from about 14.5% to about 45%,alternatively from about 15% to about 40%, alternatively from about 15%to about 25%, alternatively from about 0.1% to about 10%, andalternatively from about 15% to about 20% cotton, by weight of thesubstrate. The cotton may be devoid of chlorine. The cotton may beorganic cotton. The cotton may not be bleached. The cotton may be freeor substantially free of visual foreign matter, including cotton leaves,stalk, and/or other plant matter that has not been fully removed fromthe cotton fiber. The average visual foreign matter (VFM) <9 mm² perlinear meter of the substrate may be from about 0.001 VFM to about 0.05VFM, alternatively from about 0.005 VFM to about 0.03 VFM, alternativelyfrom about 0.007 VFM to about 0.02 VFM, and alternatively from about0.009 VFM to about 0.015 VFM, when the width of the substrate is 3meters, using a web inspection vision system which may be available fromCognex.

The substrate described herein may comprise from about 5% to about 50%,alternatively from about 10% to about 30%, alternatively from about 5%to about 25%, alternatively from about 10% to about 20%, andalternatively about 15% viscose, by weight of the substrate.

The substrate described herein may comprise from about 14.5% to about20% cotton by weight of the substrate, from about 10% to about 20%viscose by weight of the substrate, and from about 60% to about 80%polyester by weight of the substrate.

Any additional fibers of the substrate may be comprised of any natural,cellulosic, and/or wholly synthetic material. The substrate may comprisefrom about 5% to about 85%, alternatively from about 10% to about 65%,alternatively from about 15% to about 45%, alternatively from about 20to about 35%, alternatively from about 0.1% to about 30%, alternativelyfrom about 0.5% to about 5%, and alternatively from about 0.01% to about1% of the additional fibers, by weight of the substrate. Examples ofnatural fibers may include cellulosic natural fibers, such as fibersfrom hardwood sources, softwood sources, or other non-wood plants. Thenatural fibers may comprise cellulose, starch and combinations thereof.Non-limiting examples of suitable cellulosic natural fibers include woodpulp, typical northern softwood Kraft, typical southern softwood Kraft,typical CTMP, typical deinked, corn pulp, acacia, eucalyptus, aspen,reed pulp, birch, maple, radiata pine and combinations thereof. Othersources of natural fibers from plants include albardine, esparto, wheat,rice, corn, sugar cane, papyrus, jute, reed, sabia, raphia, bamboo,sidal, kenaf, abaca, sunn, rayon (also known as viscose), lyocell,cotton, hemp, flax, ramie and combinations thereof. Yet other naturalfibers may include fibers from other natural non-plant sources, such as,down, feathers, silk, cotton and combinations thereof. The naturalfibers may be treated or otherwise modified mechanically or chemicallyto provide desired characteristics or may be in a form that is generallysimilar to the form in which they may be found in nature. Mechanicaland/or chemical manipulation of natural fibers does not exclude themfrom what are considered natural fibers with respect to the developmentdescribed herein.

The synthetic fibers may be any material, such as those selected fromthe group consisting of polyesters (e.g., polyethylene terephthalate),polyolefins, polypropylenes, polyethylenes, polyethers, polyamides,polyesteramides, polyvinylalcohols, polyhydroxyalkanoates,polysaccharides, and combinations thereof. Further, the synthetic fibersmay be a single component (i.e., single synthetic material or mixturemakes up entire fiber), bi-component (i.e., the fiber is divided intoregions, the regions including two or more different synthetic materialsor mixtures thereof and may include co-extruded fibers and core andsheath fibers) and combinations thereof. Bicomponent fibers may be usedas a component fiber of the structure, and/or they may be present to actas a binder for the other fibers present in the fibrous structure. Anyor all of the synthetic fibers may be treated before, during, or aftermanufacture to change any desired properties of the fibers. Thesubstrate may comprise hydrophilic fibers, hydrophobic fibers, or acombination thereof.

The substrate may comprise various percentages of natural and/orsynthetic fibers. For example, the substrate may comprise 100% syntheticfibers. The substrate may comprise natural and synthetic fibers. Forexample, the substrate may comprise from about 0% to about 95% naturalfibers, with the balance comprising synthetic fibers.

It may be desirable to have particular combinations of fibers to providedesired characteristics. For example, it may be desirable to have fibersof certain lengths, widths, coarseness or other characteristics combinedin certain layers, or separate from each other. The fibers may be ofvirtually any size and may have an average length from about 1 mm toabout 60 mm. Average fiber length refers to the length of the individualfibers if straightened out. The fibers may have an average fiber widthof greater than about 5 micrometers. The fibers may have an averagefiber width of from about 5 micrometers to about 50 micrometers. Thefibers may have a coarseness of greater than about 5 mg/100 m. Thefibers may have a coarseness of from about 5 mg/100 m to about 75 mg/100m.

The fibers may be circular in cross-section, dog-bone shape, delta(i.e., triangular cross section), trilobal, ribbon, or other shapestypically produced as staple fibers. Likewise, the fibers may beconjugate fibers such as bicomponent fibers. The fibers may be crimpedand may have a finish, such as a lubricant, applied.

The substrate materials may also be treated to improve the softness andtexture thereof. The substrate may be subjected to various treatments,such as physical treatment, hydro-molding, hydro-embossing, and ringrolling, as described in U.S. Pat. No. 5,143,679; structural elongation,as described in U.S. Pat. No. 5,518,801; consolidation, as described inU.S. Pat. Nos. 5,914,084; 6,114,263; 6,129,801 and 6,383,431; stretchaperturing, as described in U.S. Pat. Nos. 5,628,097; 5,658,639; and5,916,661; differential elongation, as described in U.S. Pat. No.7,037,569, and other solid state formation technologies as described inU.S. Pat. No. 7,553,532 and U.S. Pat. No. 7,410,683; zone activation,and the like; chemical treatment, such as rendering part or all of thesubstrate hydrophobic, and/or hydrophilic, and the like; thermaltreatment, such as thermal-embossing, softening of fibers by heating,thermal bonding and the like; and combinations thereof.

Without wishing to be bound by theory, it is believed that a texturedsubstrate may further enable the ease of removal of soils by improvingthe ability to grip or otherwise lift the soils from the surface duringcleansing. Any one of a number of texture elements may be useful inimproving the ability to grip or otherwise lift the soil from thesurface during cleansing such as continuous hydro-molded elements,hollow molded element, solid molded elements, circles, squares,rectangles, ovals, ellipses, irregular circles, swirls, curly cues,cross hatches, pebbles, lined circles, linked irregular circles, halfcircles, wavy lines, bubble lines, puzzles, leaves, outlined leaves,plates, connected circles, changing curves, dots, honeycombs, and thelike, and combinations thereof. The texture elements may be hollowelements. The texture elements may be connected to each other. Thetexture elements may overlap each other.

The substrate may have a basis weight between about 15, 30, 40, 45 or 52grams/m² and about 65, 75, 85, 95, or 100 grams/m². Exemplary nonwovensubstrates are described in U.S. Patent Publication 2012/066852 and U.S.Patent Publication U.S. 2011/244199.

The surface of the substrate may be essentially flat. The surface of thesubstrate may optionally contain raised and/or lowered portions. Theraised and/or lowered portions may be in the form of logos, indicia,trademarks, geometric patterns, and/or images of the surfaces that thesubstrate is intended to clean (i.e., infant's body, face, etc.). Theraised and/or lowered portions may be randomly arranged on the surfaceof the substrate or be in a repetitive pattern of some form.

The substrate may be biodegradable. For example, the substrate could bemade from a biodegradable material such as a polyesteramide, or a highwet strength cellulose. The substrate may be dispersible.

The wet wipes described herein may have different properties ondifferent sides of the wet wipe. For example, one side of the wipe mayhave good cleaning performance and the other side of the wet wipe mayhave good tactile sensation to the user. In another example, one side ofthe wet wipe may have an increased cleaning performance as compared tothe other side of the wet wipe.

Non-limiting examples of processes for making fibrous structure of thesubstrate described herein include known wet-laid papermaking processes,air-laid papermaking processes including carded and/or spunlacedprocesses. Such processes typically include steps of preparing a fibercomposition in the form of a suspension in a medium, either wet, morespecifically aqueous medium, or dry, more specifically gaseous, i.e.with air as medium. The aqueous medium used for wet-laid processes isoftentimes referred to as a fiber slurry. The fibrous slurry is thenused to deposit a plurality of fibers onto a forming wire or belt suchthat an embryonic fibrous structure is formed, after which drying and/orbonding the fibers together results in a fibrous structure. Furtherprocessing the fibrous structure may be carried out such that a finishedfibrous structure is formed. For example, in typical papermakingprocesses, the finished fibrous structure is the fibrous structure thatis wound on the reel at the end of papermaking, and may subsequently beconverted into a finished product, e.g. a sanitary tissue product.

The fibrous structures of the substrate described herein may behomogeneous or may be layered. If layered, the substrate may comprise atleast two and/or at least three and/or at least four and/or at leastfive layers.

The fibrous structure of the substrate described herein may be aco-formed fibrous structure.

“Co-formed fibrous structure” as used herein means that the fibrousstructure comprises a mixture of at least two different materialswherein at least one of the materials comprises a filament, such as apolypropylene filament, and at least one other material, different fromthe first material, comprises a solid additive, such as a fiber and/or aparticulate. In one example, a co-formed fibrous structure comprisessolid additives, such as fibers, such as wood pulp fibers and/orabsorbent gel materials and/or filler particles and/or particulate spotbonding powders and/or clays, and filaments, such as polypropylenefilaments.

“Solid additive” as used herein means a fiber and/or a particulate.

“Particulate” as used herein means a granular substance or powder.

“Fiber” and/or “Filament” as used herein means an elongate particulatehaving an apparent length greatly exceeding its apparent width, i.e. alength to diameter ratio of at least about 10. For purposes of thepresent disclosure, a “fiber” is an elongate particulate as describedabove that exhibits a length of less than 5.08 cm (2 in.) and a“filament” is an elongate particulate as described above that exhibits alength of greater than or equal to 5.08 cm (2 in.).

The substrate described herein may be subjected to any post-processingoperations such as embossing operations, printing operations,tuft-generating operations, thermal bonding operations, ultrasonicbonding operations, perforating operations, surface treatment operationssuch as application of lotions, silicones and/or other materials,folding, and combinations thereof.

Wet Wipe Odor Management Material

The wet wipe described herein may employ an odor management material.The odor management material may be a naturally derived odor managementmaterial. The naturally derived odor management material may manageodors inherit to the raw materials used in the manufacture of the wetwipe and/or manage odors associated with wet wipe (e.g., urine, feces,etc). The naturally derived odor management material may include plantextracts and/or odor adsorbing materials such as silicas and zeolites.Exemplary plant extracts may include Extrapone Marigold GW and/orExtrapone Magnolia GW from Symrise. The naturally derived odormanagement material may be substantially scent-free.

Article of Commerce

An article of commerce may comprise a package and a plurality of the wetwipes described herein.

The package may comprise one or more communications that the wet wipeand/or the substrate described herein comprises cotton and/or is devoidof chlorine. The package may comprise a seal of cotton trademarked logo.The package may comprise one or more communications that the wet wipeand/or the lotion described herein is devoid of fragrance and/orperfume. The package may comprise one or more communications that thewet wipe and/or the lotion described herein comprises 99% water. Thepackage may comprise one or more communications that the wet wipe and/orthe substrate described herein is devoid of phthalate. The package maycomprise one or more communications that the wet wipe and/or the lotiondescribed herein is devoid of alcohol and/or comprises a plant extract.The package may comprise one or more communications that the wet wipeand/or lotion described herein is hypoallergenic. The package maycomprise one or more communications that the wet wipe and/or lotiondescribed herein is devoid of phenoxyethanol. The package may compriseone or more communications that the wet wipe and/or lotion describedherein is “natural” or “all natural.”

The package may be in the form of a container. Containers may include,but are not limited to, tubs, flow wrap pouches, individual sachets,chained sachets comprising a tear line between each sachet, and otherforms known in the art as suitable for storing nonwoven articles.Additionally, the container may also be manufactured to facilitateremoval of individual wet wipes.

The container may be made of any suitable material or materials and maybe manufactured in any suitable manner. For example, the container maybe made of polystyrene, polypropylene, PET, POET, polyethylene,polyester, polyvinyl alcohol, or the like. The container may also bemade of a mixture of the above materials. The container may be made of ametal foil. The container may be manufactured by, for example, a vacuummolding process or an injection molding process, or any suitableprocess.

Additional information on containers, as well as additional optionalcomponents for containers, including, but not limited to: containerbodies, lids, container features, such as, but not limited to,attachment of lids, hinges, zippers, securing aids, and the like, may befound in U.S. Pat. Nos. Des. 451,279; Des. 437,686; Des. 443,508; Des443,451; Des 421,901; Des 421,902; Des 416,794; Des 414,637; Des445,329; 3,982,659; 3,967,756; 3,986,479; 3,994,417; 6,269,970;5,785,179; 5,366,104; 5,322,178; 5,050,737; 4,971,220; 6,296,144;6,315,114; 4,840,270; 4,471,881; 5,647,506; 6,401,968; 6,269,969;6,412,634; 5,791,465; 6,092,690; U.S. Patent Application Publication No.2002/0064323 published on May 30, 2002, issued to Chin; and WO 00/27268published on May 18, 2000 and assigned to The Procter & Gamble Company;WO 02/14172 published on Feb. 21, 2002 and assigned to The Procter &Gamble Company; and WO 99/55213 published on Nov. 4, 1999 and assignedto The Procter & Gamble Company.

Test Methods

All test methods are carried out in an environment 23±2° C. and 50±5%relative humidity environment unless otherwise specified.

Lotion Expression Method

Lotion is expressed from wet wipes for further analysis using the LotionExpression Method. In this method, lotion is extracted from one or morelike packages of lotioned wipes that have been wetted in a sealedpackage for at least 28 days at 40° C. and 75% relative humidity inorder to collect a desired quantity of lotion for further analysis.

One corner is cut from one sealed wipes package to create a small(approximately 0.25-inch in diameter) hole from which liquid can escape.The package is then positioned between the platens of a uniaxial presswith the corner containing the hole for liquid escape hanging outsidethe edge of the platens such that lotion can be collected in a suitablecontainer as pressure is applied. Pressure is then increasingly appliedto the package of wipes and held at 100±10 psi for at least a minute anduntil no more fluid drains freely from the compressed lotion package, atwhich point the container holding the collected lotion is sealed tightlyuntil further analysis. This process is repeated until the desiredquantity of lotion for further analysis has been collected. If lotion iscollected from more than one package of like wipes, all lotion expressedfrom all like packages is mixed prior to any analysis.

If lotioned wipes are packaged directly in packaging that is notamenable to the pressure/deformation required by this method, lotionedwipes are removed from packaging and are immediately transferred to aclean rectangular plastic bag and sealed. The rectangular plastic bag isthen cut at one corner and placed in the platens of a press and squeezedas specified above.

Water Content Method

In the Water Content Method, a portion of expressed lotion is placed inan oven to facilitate evaporation, and the remaining unevaporated massis measured. From this, the water content of the starting expressedlotion is calculated.

The Lotion Expression Method is used to express lotion, from which a5.0±0.1 g aliquot is taken and placed in a 70-mm diameter aluminumweighing boat (such as VWR part number 25433-089, VWR International,Radmor, Pa., USA, or equivalent), and the initial mass of the lotionaliquot is determined to at least the nearest 0.001 g. Immediatelyfollowing weighing, the weighing boat containing the lotion is placed inan oven held at 100° C. for 12±1 hour, at which point the boatcontaining the unevaporated material remaining from the aliquot isremoved, and the mass of unevaporated material is determined to thenearest 0.001 g. The quotient of the unevaporated mass remaining fromthe lotion aliquot to the initial mass of the lotion aliquot, expressedas a percent to the nearest tenth of a percent, is defined as the LotionPercent Solids Parameter. The Lotion Percent Solids Parameter issubtracted from 100.0%, and the resulting difference is defined as theLotion Percent Water Parameter.

Buffering Capacity Test Method

In the Buffering Capacity Test Method, the mass of base solutionrequired to bring a specified mass of lotion to a characteristicequivalence point is measured and expressed as a ratio of mass of addedbase to initial mass of lotion, and this dimensionless ratio is definedas the Equivalence Value.

The Lotion Expression Method is used to express 40.0±0.1 g of lotion.The pH of the lotion is measured to the nearest 0.01 unit of pH with apH meter. If the pH of the lotion is equal to or greater than 10.00, theEquivalence Value is defined as 0. Otherwise, 0.1 N sodium hydroxide isadded to the initial 40.0±0.1 g of expressed lotion with stirring and pHis measured and recorded as a function of added volume of base to thenearest 0.01 until the pH reaches 10.00. The pH versus mass 0.1 N sodiumhydroxide added data are then examined, and the mass of added base atwhich the rate of change of pH with respect to addition of base is at amaximum is found and recorded in grams to the nearest 0.01 g as theEquivalence Mass. The Equivalence Mass divided by the initial mass ofexpressed lotion (40.0±0.1 g), then multiplied by 100, is defined as theEquivalence Value, reported to the hundredths place in dimensionlessunits.

Substrate Cellulosic Fiber Content Test Method

The content of cellulosic fibers (e.g. cotton, viscose rayon) of the wetwipe substrate is determined using common methods known to those ofskill in the art to both identify the identity of fibers present and tochoose an appropriate method for relative quantification. For example,ISO 1833-1977 can be used to quantify a variety of common mixtures offibers, and in particular, section 10, Mixtures of Cellulose andPolyester Fibres, can be used to determine the content of cellulosicfibers in the presence of polyester fibers.

Organic Acid Content Test Methods

The weight percent of organic acid and the corresponding deprotonatedconjugate base in the wet wipe lotion composition is determined usingtypical chemical analytical methods known to those skilled in the art.One example of determining the content of benzoic acid and conjugatebase benzoate ion via High Pressure Liquid Chromatography (HPLC) is asfollows.

In this method, HPLC performed using a mobile phase at a pH ofapproximately 2 is used to determine the content of total benzoatespecies of expressed wet wipe lotion. Here, total benzoate speciesrefers to the presence of both benzoic acid and its conjugate basebenzoate ion. The use of a mobile phase with a pH (pH approx. 2)significantly below the pKa of benzoic acid (pKa=4.2) results inessentially all benzoate species being in the form of benzoic acid,which is directly measured via HPLC separation and detection. The HPLCresult can then be used together with the measured pH of expressedlotion to calculate the content of benzoic acid in the expressed lotion.

An HPLC instrument (such as Waters 2695, Waters Corporation, Milford,Mass., USA, or equivalent) is configured for isocratic separation with aflow rate of 1.5 mL/min, an injection volume of 10 μL, a columntemperature of 35±1° C., and UV detection at a wavelength of 254 nm. Anoctadecyl reversed-phase silica column, 4.6×100 mm, particle size 3 or3.5 μm, (such as Waters SunFire C18, part number #186002553, orequivalent) is used. A guard column (such as Phenomenex SecurityGuardCartridges C18 4×2 mm, part number #AJ0-4286, Phenomenex Inc., Torrence,Calif., USA, or equivalent) is recommended.

A phosphoric acid buffer mobile phase solution is prepared by adding3.8±0.1 g of monosodium phosphate and 3.2±0.1 g of 85-90% phosphoricacid to 1300 mL of HPLC grade water and 325 mL of acetonitrile. Fivestandard solutions of benzoic acid are prepared using the mobile phasesolution using class A volumetric pipettes and flasks with levels(precisely known) of approximately 20, 40, 100, 200, and 300 μg/mL.

The Lotion Expression Method is used to express all lotion from onepackage of wipes. (If this lotion is less than 50 mL in volume, theLotion Expression Method is used to express lotion from additional likepackages of wipes until the volume of expressed lotion exceeds 50 mL.)The pH of the quantity of lotion expressed is measured and recorded tothe nearest 0.01 unit of pH. From the quantity of lotion expressed isweighed a sample 5.0±0.1 g (mass recorded to the nearest 0.1 mg), whichis added to a 50 mL volumetric flask and diluted to volume with mobilephase. The ratio of sample mass to dilution volume, expressed in unitsof μg/mL, is defined as the dilution factor. This resulting solution isreferred to as the sample as prepared. (If, after injection of standardsand sample as prepared, it is found that the benzoic acid content of thesample as prepared lies outside the range of standards, another sampleis prepared as above but adjusting the dilution such that the benzoicacid content lies within the range of benzoic acid standards, and arevised dilution factor is recorded.)

All five standards and the prepared sample are injected sequentiallyinto the HPLC instrument. (Given the separation conditions specified,the benzoic acid peak generally occurs at around 5.5 minutes of elutiontime, but its exact position is confirmed via position in thestandards.) A calibration curve of benzoic acid peak area versus benzoicacid concentration is fitted linearly to the peak areas of the fivestandards, and this linear fit is used to calculate the concentration(in μg/mL) benzoic acid in the sample as prepared, and this value isrecorded to the nearest 0.1 μg/mL. The concentration of benzoic acid inthe sample as prepared is then multiplied 100% and divided by thedilution factor to arrive at the weight percent of total benzoatespecies in the expressed lotion.

The measured pH of the expressed lotion is then used to determine howmuch of total benzoate species exists as benzoic acid at the pH of theexpressed lotion. The ratio of benzoic acid to benzoate ion is found bythe following equation:

${{ratio}\mspace{14mu} {of}\mspace{14mu} {benzoic}\mspace{14mu} {acid}\mspace{14mu} {to}\mspace{14mu} {benzoate}} = \frac{10^{- {pH}}}{10^{- {pk}_{a}}}$

And from this ratio, the weight percent of benzoic acid in the expressedlotion is found by the following equation.

${{Weight}\mspace{14mu} \% \mspace{14mu} {benzoic}\mspace{14mu} {acid}\mspace{14mu} {in}\mspace{14mu} {expressed}\mspace{14mu} {lotion}} = \frac{{weight}\mspace{14mu} \% \mspace{14mu} {total}\mspace{14mu} {benzoate}\mspace{14mu} {species}\mspace{14mu} {in}\mspace{14mu} {expressed}\mspace{14mu} {lotion}}{\left( {1 + \frac{1}{{ratio}\mspace{14mu} {of}\mspace{14mu} {benzoic}\mspace{14mu} {acid}\mspace{14mu} {to}\mspace{14mu} {benzoate}}} \right)}$

Microbiological Susceptibility Test Method

The Microbiological Susceptibility Test Method is used to determine theMST Yeast & Mold Value. The Microbiological Susceptibility Test Methodfollows United States Pharmacopoeia

51

Antimicrobial Effectiveness Testing and specifically follows theprocedures for yeast and mold challenge of Category 2 products. Theinoculation procedure is modified for application to wetted wipes asfollows.

For each sample prepared, an entire previously sealed, unopened packageof wetted wipes is opened, and 10.0±1.0 g of wipes is removed from asclosely as possible to the middle of the stack of wipes and isaseptically weighed into a sterile container. Wipes are cut, if needed,in order for the sample to meet the mass target. Inoculums of yeast(Candida albicans) and mold (Aspergillus brasiliensis) are mixed in a1:1 ratio to form a mixed inoculum. Prior to inoculation, the mixedyeast and mold inoculum is further diluted from the recommended level1:10 in sterile 0.85% NaCl (w/w) saline solution. 1.0±0.1 mL of thisresulting diluted inoculum is then spread as uniformly as is feasibleacross the wipes sample. Inoculated samples are stored at 22.5±2.5° C.until sampling. At the time of sampling, each wipes sample is added to90 mL of liquid growth medium and is homogenized for two minutes at 260RPM using a stomacher (such as the Stomacher 400 Circulator, SewardLtd., West Sussex, UK, or equivalent). Additional 1:10 dilutions areperformed using liquid growth medium (to achieve 1:100, 1:1000 dilutionsand so on) as needed to enable a meaningful plate count. Plate countsare performed on 100-mm diameter petri plates, and ideal CFU readingsfor plates are between 25 and 250 for yeast and between 8 and 80 formold. For each microorganism, the lowest dilution factor that leads to araw CFU reading that falls within the allowed range is ideally used tocalculate CFU/mL of survivors.

Using the determined starting and surviving concentration of eachmicroorganism, as determined by USP (51), further quantities are definedand calculated. The Starting Yeast and Mold Concentration is defined asthe sum of starting concentrations (in CFU/mL) for each of themicroorganisms of yeast and mold analyzed. The Pooled Yeast and MoldConcentration at 28 Days is defined as the sum of measured concentration(in CFU/mL) of survivors for each of the microorganisms of yeast andmold analyzed.

The ratios of pooled microorganism count at 28 days versus the startingpooled microorganism count are used to calculate the MST Yeast & MoldValue. The MST Yeast & Mold Value is defined as

${{{{MST}\mspace{14mu} {Yeast}}\&}\mspace{11mu} {Mold}\mspace{14mu} {Value}} - {\log_{10}\frac{{Pooled}\mspace{14mu} {Yeast}\mspace{14mu} {and}\mspace{14mu} {Mold}\mspace{14mu} {Concentration}\mspace{14mu} {at}\mspace{14mu} 28\mspace{14mu} {Days}}{{Starting}\mspace{14mu} {Pooled}\mspace{14mu} {Yeast}\mspace{14mu} {and}\mspace{14mu} {Mold}\mspace{14mu} {Concentration}}}$

and is reported to the nearest tenth of a log unit.

EXAMPLES & DATA

The following examples and comparative examples are provided to helpillustrate the lotion described herein. The exemplified lotions may beprepared by conventional formulation and mixing techniques. It will beappreciated that other modifications of the lotions described hereinwithin the skill of those in the formulation art may be undertaken. Allparts, percentages, and ratios herein are by weight unless otherwisespecified. Some components may come from suppliers as dilute solutions.The amount stated reflects the weight percent of the active material,unless otherwise specified.

Examples 1-10 in Tables 1 and 2 show exemplary and comparative lotionformulations.

TABLE 1 Ingredient Ex. 1 Ex. 2 Ex. 3 Ex. 4 Ex. 5 Water 99.018 98.93199.038 98.527 98.834 PEG-40 HCO 0.16 0.16 0.16 0.20 0.16 SorbitanCaprylate 0.16 0.16 0.1 0.20 0.16 Trisodium Citrate 0.290 0.203 0.2030.320 0.141 Dihydrate Sodium Benzoate 0.18 0.18 0.18 0.20 0.22 DisodiumEDTA 0.10 0.10 0.10 0.10 0.10 Citric Acid 0.092 0.266 0.159 0.450 0.385Anhydrous pH 3.8 4.2 4.6 4.0 3.8

TABLE 2 Ingredient Ex. 6 Ex. 7 Ex. 8 Ex. 9 Ex. 10 Water 98.995 99.09098.802 98.958 99.069 PEG-40 HCO 0.16 0.16 0.16 0.16 0.16 SorbitanCaprylate 0.16 0.16 0.16 0.16 0.16 Trisodium Citrate 0.141 0.141 0.1400.140 0.140 Dihydrate Sodium Benzoate 0.22 0.22 0.24 0.24 0.24 DisodiumEDTA 0.10 0.10 0.10 0.10 0.10 Citric Acid 0.224 0.130 0.398 0.242 0.132Anhydrous pH 4.2 4.6 3.8 4.2 4.6

Examples 1-10 were made by the following formulation steps, all of whichwere performed at a temperature of 20-25° C.:

-   -   1. Create a 1:1 premix of PEG 40 hydrogenated castor oil and        sorbitan caprylate, mixing with an IKA ULTRA-TURRAX® (for        example model T-50 with a S 50 N-W 80 SMK jet mixer head) or        equivalent mixer for 10 minutes at 5000-6000 rpm.    -   2. Add distilled, deionized water to the mixing vessel and start        the mixing with the same mixer and speed as in step 1,        maintaining this mixing throughout the entire process.    -   3. Add trisodium citrate dihydrate, mix 15 seconds, add sodium        benzoate, mix 1 minute, add disodium EDTA, mix 1 minute.    -   4. Add PEG 40 hydrogenated castor oil and sorbitan caprylate        premix slowly to the mixing vessel, taking 15-20 seconds to add        and allow for incorporation. Mix for 2 minutes.    -   5. Add citric acid anhydrous.    -   6. Optionally add odor reduction composition.    -   7. Mix for 10 minutes.    -   8. Stop mixing. Confirm final pH is within desired range, e.g.        target pH+/−0.1.

Table 3 shows MST Yeast & Mold Value measurements obtained from Examples1-10 in Tables 1 and 2. The MST Yeast & Mold Value measurements weretaken using the Microbiological Susceptibility Test Method providedherein. The higher the MST Yeast & Mold Value, the greater thepreservation robustness of the wet wipe against yeast and mold growth.

TABLE 3 % Benzoic % Sodium MST Yeast & MST Yeast & Acid Benzoate MoldValue Mold Value Example in Lotion in Lotion Day 14 Day 28 1 0.061 0.0243.5 4.2 2 0.053 0.053 3.3 3.7 3 0.038 0.093 2.0 2.7 4 0.066 0.041 3.84.0 5 0.077 0.030 4.5 4.5 6 0.067 0.066 4.2 4.2 7 0.047 0.118 2.3 2.6 80.084 0.033 4.5 4.5 9 0.072 0.072 4.2 4.5 10 0.053 0.131 2.3 3.4

The wet wipes described herein may have an MST Yeast & Mold Value at day28 of from about 3 to about 5, alternatively from about 3.4 to about4.8, alternatively from about 3.8 to about 5, alternatively from about3.9 to about 4.7, and alternatively from about 4 to about 4.5, accordingto the Microbiological Susceptibility Test Method provided herein. Thewet wipes described herein may have an MST Yeast & Mold Value at day 14of from about 2.3 to about 5, alternatively from about 3 to about 5,alternatively from about 3.4 to about 4.8, alternatively from about 3.5to about 4.5, alternatively from 4.2 to about 4.7, and alternativelyfrom about 4 to about 4.5, according to the MicrobiologicalSusceptibility Test Method provided herein.

Examples 11-15 in Table 4 show additional examples of lotionformulations as described herein.

TABLE 4 Ingredient Ex. 11 Ex. 12 Ex. 13 Ex. 14 Ex. 15 Water 99.01898.527 98.834 98.995 98.722 PEG-40 HCO 0.16 0.20 0.16 0.16 0 GlycerylCaprylate 0.16 0.20 0.16 0.16 0 Trisodium Citrate 0.290 0.320 0.1410.141 0.140 Dihydrate Sodium Benzoate, 0.18 0.20 0.22 0.22 0.64 SodiumGluconate, Sodium Levulinate, Sodium Anisate or mixtures thereofDisodium EDTA or 0.10 0.10 0.10 0.10 0.10 Sodium Gluconate Citric Acid0.092 0.450 0.385 0.224 0.398 Anhydrous pH 3.8 4.0 3.8 4.2 3.8

Additional Examples/Combinations

-   A. A wet wipe comprising a substrate and a lotion, wherein the    substrate comprises from about 55% to about 85% polyester by weight    of the substrate, and wherein the lotion comprises:    -   a) from about 98.5% to about 99.5% water by weight of the        lotion;    -   b) from about 0.055% to about 0.1% of an organic acid according        to a HPLC test method described herein; and    -   c) a pH buffering system;    -   wherein the lotion has a pH from about 3.6 to about 4.8.-   B. The wet wipe according to paragraph A, wherein the substrate    further comprises about 14.5% to about 45% cotton by weight of the    substrate.-   C. The wet wipe according to paragraph B, wherein the cotton is    devoid of chlorine.-   D. A package comprising the wet wipe according to paragraph C,    wherein the package comprises one or more communications that the    substrate comprises cotton and/or is devoid of chlorine.-   E. The wet wipe according to any of paragraphs A-D, wherein the    lotion is devoid of fragrance and/or perfume.-   F. A package comprising the wet wipe according to paragraph E,    wherein the package comprises one or more communications that the    lotion is devoid of fragrance and/or perfume.-   G. A package comprising the wet wipe according to any of paragraphs    A-F, wherein the package comprises one or more communications that    the lotion comprises 99% water.-   H. A package comprising the wet wipe according to paragraph B,    wherein the package comprises a seal of cotton trademarked logo.-   I. The wet wipe according to any of paragraphs A-H, wherein the wet    wipe comprises an MST Yeast & Mold Value at day 28 of from about 3.4    to about 4.8.-   J. The wet wipe according to any of paragraphs A-I, wherein the wet    wipe further comprises a naturally derived odor management material.-   K. The wet wipe according to paragraph J, wherein the naturally    derived odor management material is substantially scent-free.-   L. A wet wipe comprising a substrate and a lotion, wherein the    substrate comprises from about 55% to about 85% polyester by weight    of the substrate, wherein the substrate comprises from about 14.5%    to about 45% cotton by weight of the substrate, wherein the lotion    comprises from about 98.5% to about 99.5% water by weight of the    lotion, and wherein the lotion has an Equivalence Point from about    10 to about 50.-   M. The wet wipe according to paragraph L, wherein the cotton is    devoid of chlorine.-   N. A package comprising the wet wipe according to paragraph M,    wherein the package comprises one or more communications that the    substrate comprises cotton and/or is devoid of chlorine.-   O. The wet wipe according to any of paragraphs L-N, wherein the    lotion is devoid of fragrance and/or perfume.-   P. A package comprising the wet wipe according to paragraph O,    wherein the package comprises one or more communications that the    lotion is devoid of fragrance and/or perfume.-   Q. A package comprising the wet wipe according to any of paragraphs    L-P, wherein the package comprises a seal of cotton trademarked    logo.-   R. A package comprising a plurality of wet wipes, wherein the    plurality of wet wipes each comprise a substrate and a lotion,    wherein the substrate comprises:    -   a) from about 55% to about 85% polyester by weight of the        substrate; and    -   b) from about 14.5% to about 45% cotton by weight of the        substrate;    -   wherein the cotton is devoid of chlorine;    -   wherein the lotion comprises:    -   a) from about 98.5% to about 99.5% water by weight of the        lotion;    -   b) from about 0.055% to about 0.1% of an organic acid according        to a HPLC test method described herein; and    -   c) from about 0.4% to about 1% of a pH buffering system by        weight of the lotion;    -   wherein the organic acid is selected from the group consisting        of anisic acid, malic acid, lactic acid, dehydroacetic acid,        gluconic acid, salicylic acid, benzoic acid, sorbic acid,        levulinic acid, and mixtures thereof;    -   wherein the lotion has a pH from about 3.6 to about 4.4;    -   wherein the lotion has an Equivalence Point from about 15 to        about 40; and    -   wherein the lotion is devoid of fragrance and/or perfume.-   S. The package according to paragraph R, wherein the substrate is    devoid of phthalate.-   T. The package according to paragraph S, wherein the package    comprises one or more communications that the substrate comprises    cotton, is devoid of chlorine, is devoid of perfume, and/or is    devoid of phthalate.-   U. The package according to any of paragraphs R-T, wherein the    organic acid is benzoic acid.-   V. The package according to any of paragraphs R-U, wherein the    polyester comprises less than 100 ppm antimony.

The dimensions and values disclosed herein are not to be understood asbeing strictly limited to the exact numerical values recited. Instead,unless otherwise specified, each such dimension is intended to mean boththe recited value and a functionally equivalent range surrounding thatvalue. For example, a dimension disclosed as “40 mm” is intended to mean“about 40 mm.”

Every document cited herein, including any cross referenced or relatedpatent or application and any patent application or patent to which thisapplication claims priority or benefit thereof, is hereby incorporatedherein by reference in its entirety unless expressly excluded orotherwise limited. The citation of any document is not an admission thatit is prior art with respect to any invention disclosed or claimedherein or that it alone, or in any combination with any other referenceor references, teaches, suggests or discloses any such invention.Further, to the extent that any meaning or definition of a term in thisdocument conflicts with any meaning or definition of the same term in adocument incorporated by reference, the meaning or definition assignedto that term in this document shall govern.

While particular embodiments of the present invention have beenillustrated and described, it would be obvious to those skilled in theart that various other changes and modifications may be made withoutdeparting from the spirit and scope of the invention. It is thereforeintended to cover in the appended claims all such changes andmodifications that are within the scope of this invention.

What is claimed is: 1) A wet wipe comprising a substrate and a lotion,wherein the substrate comprises from about 55% to about 85% polyester byweight of the substrate, and wherein the lotion comprises: a) from about98.5% to about 99.5% water by weight of the lotion; b) from about 0.055%to about 0.1% of an organic acid according to a HPLC test methoddescribed herein; and c) a pH buffering system; wherein the lotion has apH from about 3.6 to about 4.8. 2) The wet wipe of claim 1, wherein thesubstrate further comprises about 14.5% to about 45% cotton by weight ofthe substrate. 3) The wet wipe of claim 2, wherein the cotton is devoidof chlorine. 4) A package comprising the wet wipe of claim 3, whereinthe package comprises one or more communications that the substratecomprises cotton and/or is devoid of chlorine. 5) The wet wipe of claim1, wherein the lotion is devoid of fragrance and/or perfume. 6) Apackage comprising the wet wipe of claim 5, wherein the packagecomprises one or more communications that the lotion is devoid offragrance and/or perfume. 7) A package comprising the wet wipe of claim1, wherein the package comprises one or more communications that thelotion comprises 99% water. 8) A package comprising the wet wipe ofclaim 2, wherein the package comprises a seal of cotton trademarkedlogo. 9) The wet wipe of claim 1, wherein the wet wipe comprises an MSTYeast & Mold Value at day 28 of from about 3.4 to about 4.8. 10) The wetwipe of claim 1, wherein the wet wipe further comprises a naturallyderived odor management material. 11) The wet wipe of claim 10, whereinthe naturally derived odor management material is substantiallyscent-free. 12) A wet wipe comprising a substrate and a lotion, whereinthe substrate comprises from about 55% to about 85% polyester by weightof the substrate, wherein the substrate comprises from about 14.5% toabout 45% cotton by weight of the substrate, wherein the lotioncomprises from about 98.5% to about 99.5% water by weight of the lotion,and wherein the lotion has an Equivalence Point from about 10 to about50. 13) The wet wipe of claim 12, wherein the cotton is devoid ofchlorine. 14) A package comprising the wet wipe of claim 13, wherein thepackage comprises one or more communications that the substratecomprises cotton and/or is devoid of chlorine. 15) The wet wipe of claim12, wherein the lotion is devoid of fragrance and/or perfume. 16) Apackage comprising the wet wipe of claim 15, wherein the packagecomprises one or more communications that the lotion is devoid offragrance and/or perfume. 17) A package comprising the wet wipe of claim12, wherein the package comprises a seal of cotton trademarked logo. 18)A package comprising a plurality of wet wipes, wherein the plurality ofwet wipes each comprise a substrate and a lotion, wherein the substratecomprises: a) from about 55% to about 85% polyester by weight of thesubstrate; and b) from about 14.5% to about 45% cotton by weight of thesubstrate; wherein the cotton is devoid of chlorine; wherein the lotioncomprises: a) from about 98.5% to about 99.5% water by weight of thelotion; b) from about 0.055% to about 0.1% of an organic acid accordingto a HPLC test method described herein; and c) from about 0.4% to about1% of a pH buffering system by weight of the lotion; wherein the organicacid is selected from the group consisting of anisic acid, malic acid,lactic acid, dehydroacetic acid, gluconic acid, salicylic acid, benzoicacid, sorbic acid, levulinic acid, and mixtures thereof; wherein thelotion has a pH from about 3.6 to about 4.4; wherein the lotion has anEquivalence Point from about 15 to about 40; and wherein the lotion isdevoid of fragrance and/or perfume. 19) The package of claim 18, whereinthe substrate is devoid of phthalate. 20) The package of claim 19,wherein the package comprises one or more communications that thesubstrate comprises cotton, is devoid of chlorine, is devoid of perfume,and/or is devoid of phthalate. 21) The package of claim 18, wherein theorganic acid is benzoic acid. 22) The package of claim 18, wherein thepolyester comprises less than 100 ppm antimony.